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Writer's pictureFelicity Burnell
Oct 94 min read

What is a... MIXOID CYST

Updated: Nov 29


Understanding Mixoid Cysts: Causes, Symptoms, and Treatment

A mixoid cyst is a benign, fluid-filled growth that commonly forms on toes, especially around the last joint of the toe near the nail bed. These cysts, also known as mucous cysts or digital mucous cysts, are associated with osteoarthritis and typically affect middle-aged or elderly individuals. While they are generally harmless, they can cause discomfort, cosmetic concerns, and occasionally interfere with toe mobility or nail growth.


What Are Mixoid Cysts?

Mixoid cysts are soft, round lumps that form just beneath the skin and are filled with a thick, gel-like substance known as mucin. Mucin is a type of glycoprotein produced by synovial cells in the joints. The term "mixoid" refers to the mucous-like, jelly consistency of the fluid inside the cyst. These cysts most often appear on the dorsum (top) of the toes, usually near the distal interphalangeal (DIP) joint—the last joint of the toe.

Mixoid cysts are not cancerous and do not spread to other parts of the body, but they can become symptomatic, especially if they press on surrounding tissues or the joint itself.

Causes of Mixoid Cysts

The exact cause of mixoid cysts is still not fully understood, but they are thought to be closely linked to degenerative changes in the toe joints, particularly osteoarthritis. Over time, wear and tear on the joint cartilage can lead to the formation of bone spurs, and these spurs can cause the synovial fluid to leak and accumulate in a small sac, forming the cyst. Other contributing factors include:

  1. Aging: Osteoarthritis and joint degeneration become more common with age.

  2. Joint Trauma or Injury: Prior injuries to the fingers may increase the likelihood of developing cysts.

  3. Repetitive Use: Activities that put stress on the finger joints may also contribute to cyst formation.

Symptoms of Mixoid Cysts

The primary symptom of a mixoid cyst is the appearance of a visible lump near the joint on the back of the toe. Other common symptoms include:

  • Painless or Mildly Painful Lump: The cyst is usually soft and painless but can become painful if it grows larger or presses on nearby structures.

  • Discomfort During Movement: Some people experience tenderness or discomfort when moving the affected toe.

  • Changes in the Nail: In some cases, the cyst can affect nail growth, causing nail ridging, thinning, or even separation from the nail bed.

  • Occasional Fluid Leakage: If the cyst ruptures, a clear, thick, sticky fluid may drain from it. This fluid is not dangerous but should be cleaned to avoid infection.

Diagnosis

Diagnosing a mixoid cyst is usually straightforward and based on clinical examination. A podiatrist can often identify the cyst by its appearance and location on the toe. In some cases, they may recommend additional imaging studies, such as X-rays, to assess underlying joint conditions like osteoarthritis or bone spurs that may be contributing to the cyst's formation.

Treatment Options

Most mixoid cysts are harmless and do not require medical treatment unless they cause discomfort or functional problems. However, when treatment is necessary, options include:

  1. Observation: If the cyst is small, painless, and not interfering with joint movement or nail growth, no treatment may be needed. Many mixoid cysts resolve on their own over time.

  2. Drainage: Aspiration, or draining the cyst with a needle, may be recommended to relieve pressure and reduce the cyst's size. However, this procedure has a relatively high recurrence rate, as the underlying cause (joint fluid leakage) is not addressed.

  3. Injection of Steroids: A corticosteroid injection may be used to reduce inflammation and shrink the cyst after drainage. This is often done in combination with aspiration.

  4. Surgical Removal: In cases where the cyst recurs, causes pain, or significantly affects toe movement, surgery may be recommended. During surgery, the cyst and its connection to the joint are carefully removed, reducing the likelihood of recurrence. Surgery is generally successful, but as with any procedure, there are risks of infection or scarring.

  5. Cryotherapy: Freezing the cyst can sometimes be effective in reducing its size and symptoms. However, it is less commonly used than other treatments.

  6. Laser Therapy: In some cases, laser therapy is used to break down the cyst tissue and promote healing.

Home Care and Management

For mild cases, home care can help manage the symptoms of mixoid cysts. Some suggestions include:

  • Protecting the Area: Wearing a protective bandage can help avoid further irritation or trauma to the cyst.

  • Over-the-Counter Pain Relief: If the cyst causes discomfort, nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen gel can be applied directly to the cyst to reduce pain and inflammation.

  • Avoid Popping the Cyst: It’s important not to attempt to pop or drain the cyst at home, as this can lead to infection.

Prognosis and Long-Term Outlook

Mixoid cysts are generally benign and have a good prognosis. Most do not require invasive treatment unless they cause significant discomfort or functional issues. Even though they may recur, especially after nonsurgical treatment, they rarely lead to complications beyond cosmetic concerns or mild discomfort. If associated with osteoarthritis, managing the underlying joint condition is crucial for long-term relief.

Conclusion

Mixoid cysts, although often harmless, can cause discomfort and cosmetic issues for those affected. While they are closely linked to joint degeneration, especially osteoarthritis, the outlook for treatment is positive. Surgical removal is the most definitive solution for recurrent cysts, while less invasive measures like aspiration and steroid injections can provide relief for milder cases. If you notice any changes in your toe joints or develop a cyst, consult with a podiatrist to discuss the most appropriate treatment options.


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